# Skill Revision

Computational drug-discovery agents usually rebuild their tool calls for every task, so a successful strategy rarely carries over. DrugHarness places more than 80 scientific operations and biomedical resources in one workspace, induces action hypotheses with explicit applicability conditions from execution trajectories, and admits them as skills only after an independent review agent checks sources and runs targeted trials when needed. On MolBench, the configuration without evolution reaches 91.9% affinity-comparison accuracy, 10.8 percentage points above reported MolClaw-CC results; in retrospective evaluation, frozen learned skills raise Qwen's optimization success from 79.5% to 87.2%.

Computational drug-discovery agents usually rebuild their tool calls for every task, so a successful strategy rarely carries over. DrugHarness places more than 80 scientific operations and biomedical resources in one workspace, induces action hypotheses with explicit applicability conditions from execution trajectories, and admits them as skills only after an independent review agent checks sources and runs targeted trials when needed. On MolBench, the configuration without evolution reaches 91.9% affinity-comparison accuracy, 10.8 percentage points above reported MolClaw-CC results; in retrospective evaluation, frozen learned skills raise Qwen's optimization success from 79.5% to 87.2%.