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# SAM2

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  1. Cryo-ET membrane segmentation goes two-stage: Dice rises from 0.6381 to 0.8116, at 79.97 seconds per tomogram

    Cell membrane segmentation in cryo-electron tomograms now runs through a two-stage fine-tuned pipeline: tomograms are sliced along Z and treated as video frames, and SAM2's memory encoder and memory attention track membranes across slices. Stage one produces an initial membrane prediction whose normalized logits are concatenated with the original slices before stage two emits the final mask. On 17 independent experimental tomograms with ground truth, Dice is 0.8116, IoU 0.7059, precision 0.8123 and recall 0.8430, all above Membrain-Seg and TARDIS, with AUPRC 0.8565; average runtime is 79.97 seconds per tomogram at 1312.1 MB of GPU memory.

  2. arXiv

    Crack inspection moves past pixels: IAC turns masks into millimeter widths and a continuous severity score

    Inspect Any Crack converts crack segmentation masks into millimeter-scale widths and a continuous severity score, giving 7.33% mean relative width error at 41 caliper-referenced locations so inspection images yield condition judgments that can be checked against standards.

  3. Burn-area estimation drops the scanner: frontal and dorsal masks alone beat the direct pixel-area ratio

    Total burn surface area is now regressed directly from frontal and dorsal whole-body and burn-region binary masks, cutting error below the direct pixel-area ratio baseline on a synthetic set of 5,000 human models and 320,000 rendered views.

  4. arXiv

    X-ray security scans skip human labels: mining objects from unlabeled scans lifts cluttered-bag localization by up to 23 points

    Universal object localization in X-ray security screening has been limited by scarce expert annotation, forcing reliance on RGB-pretrained segmentation models that falter on overlapping, weakly bounded baggage scans. LAO-X mines object instances from unlabeled X-ray scans, recomposes them in the absorbance domain under the Beer-Lambert law to build cluttered scenes with holistic and part pseudo-masks, then fine-tunes a SAM2 localizer through an occlusion-controlled curriculum. Across six X-ray benchmarks, it raises category-agnostic mAP over SAM2 and X-ray-specific baselines by 2% to 23% with no human-annotated labels, reaching 53.33% mAP on DET-COMPASS.

  5. bioRxiv

    Home-cage AI monitoring finds social and nest-building deficits in SPTAN1 R1098Q mice, with wild-type co-housing partially reducing hyperactivity and restoring rest patterns

    The authors built a non-invasive, high-content home-cage phenotyping framework combining SLEAP.ai markerless multi-animal pose estimation, DeepOF automated classification of autonomous and social behaviors, and SAM2 segmentation and quantification of nest-building material, and used long-term monitoring of the early infantile epileptic encephalopathy (EIEE5) model SPTAN1 R1098Q to show impaired spatial habituation in mutant-mutant pairs, persistent unreciprocated trailing of cage mates, and a pronounced reduction in nest-building, while co-housing with a wild-type littermate attenuated mutant hyperactivity and restored a more typical rest pattern.

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