Dual-agent framework PsyCIDRA raises diagnostic agreement in free-form psychiatric interviewing: 60.5% vs 51.9% rank-1 on held-out simulated cases and 79.6% vs 65.4% agreement with psychologists on whether to propose a hypothesis in a 101-participant study
The authors present PsyCIDRA, a dual-agent framework in which an interviewer agent conducts free-form psychiatric interviews using working notes, expert-written skills, and ICD-11 retrieval, and a diagnostic reasoning agent then receives only the completed transcript and reports hypotheses with supporting, conflicting, and missing evidence, withholding a final hypothesis when evidence is insufficient; across a 53-case evaluation cohort and 81 held-out simulated cases it achieves higher diagnostic agreement than direct prompting, and in a blinded study of 101 human participants it agrees with psychologists on whether to propose a diagnostic hypothesis in 79.6% versus 65.4% of cases.