# Cell line development partnership

Asimov announced a cell line development partnership with Sidewinder Therapeutics and delivered a cell line for Sidewinder's 4-chain bispecific antibody candidate for solid tumors. Such complex molecules are hard to express, and Sidewinder needed both the required expression level and consistent product quality. Asimov ran the custom program with its CHO Edge system, which combines a GS knock-out CHO host, a hyperactive transposase, a genetic parts library and Kernel, its AI-driven genetic design software; in a platform fed-batch process the cell line achieved clonal titers of over 10 g/L.

Asimov announced a cell line development partnership with Sidewinder Therapeutics and delivered a cell line for Sidewinder's 4-chain bispecific antibody candidate for solid tumors. Such complex molecules are hard to express, and Sidewinder needed both the required expression level and consistent product quality. Asimov ran the custom program with its CHO Edge system, which combines a GS knock-out CHO host, a hyperactive transposase, a genetic parts library and Kernel, its AI-driven genetic design software; in a platform fed-batch process the cell line achieved clonal titers of over 10 g/L.