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# Intracranial EEG

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  1. arXiv

    Epilepsy detection across patients with different electrode layouts: MOSAIC infers channel graphs and steadies them by self-distillation

    Intracranial EEG electrode count and placement differ from patient to patient, so detectors with a fixed channel topology generalize poorly under subject-independent evaluation. MOSAIC encodes each channel with a shared convolutional encoder, then a single channel-attention layer infers a weighted inter-channel adjacency from the encoded features without any preset montage graph; an exponential moving average self-distillation term pulls each window's adjacency toward a slowly updated per-patient teacher. Across four public iEEG corpora, MOSAIC's F2 on both the SWEC-ETHZ short-term and long-term corpora exceeds the listed baselines, by 1.8 points over the strongest baseline on the short-term corpus and 3.3 points on the long-term one.

  2. bioRxiv

    Stimulated brain responses last twice as long as textbooks say: SafeLens builds its own null from resting data and tracks cortical evoked potentials to 1,040 ms

    SafeLens pairs nonlinear machine learning with strict false-positive control for event-locked neural activity. It trains a random forest at each sliding-window position to separate event-locked trials from resting trials, then runs the same pipeline on set-aside resting recordings to build a model-matched empirical null, holding the family-wise error rate per channel. On simulated cortico-cortical evoked potentials injected into real resting intracranial EEG it resolved about 2.5 times as many polarity-resolved deflections as trial-average thresholding and the closest data-driven method, with 5 to 11 times fewer false components; in eight patients responses stayed above chance to 1,040 ms after stimulation, against 570 and 455 ms for the two benchmarks.

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