Dino U-Net, a frozen DINOv3 encoder with FAPM projection, reaches top segmentation across seven medical imaging datasets, with the 7B variant averaging 76.43% Dice
The work proposes Dino U-Net: a frozen DINOv3 foundation backbone as encoder, combined with a dual-branch DINO Adapter and a Fidelity-Aware Projection Module (FAPM), which outperforms seven baseline methods on seven public medical image datasets spanning endoscopy, ultrasound, microscopy, MRI, fundus and CMR modalities, and shows performance improving as the backbone scales from S to 7B.