Stefano Moro

This Perspective argues that chemistry and language have followed a comparable representational trajectory—from tacit practitioner knowledge to systematic symbols and then to geometric, navigable spaces—and builds on this to propose a conceptual framework in which molecular properties are interpreted as forms of chemical meaning emerging from molecular structure, treating semantic interpolation in latent spaces and alchemical transformations in molecular simulation as related strategies for navigating continuous manifolds that connect discrete chemical states, while proposing a Chemical Imitation Game as a possible framework for evaluating molecular AI beyond syntactic validity toward chemically meaningful reasoning.

This Perspective argues that chemistry and language have followed a comparable representational trajectory—from tacit practitioner knowledge to systematic symbols and then to geometric, navigable spaces—and builds on this to propose a conceptual framework in which molecular properties are interpreted as forms of chemical meaning emerging from molecular structure, treating semantic interpolation in latent spaces and alchemical transformations in molecular simulation as related strategies for navigating continuous manifolds that connect discrete chemical states, while proposing a Chemical Imitation Game as a possible framework for evaluating molecular AI beyond syntactic validity toward chemically meaningful reasoning.