VRPTR predicts individual language activation maps from resting-state fMRI and provides calibrated uncertainty estimates
The study introduces VRPTR, a three-dimensional encoder-decoder combining a compressed Transformer bottleneck, variational latent sampling, and multiscale skip connections, trained on 360 healthy adults from the WU-Minn Human Connectome Project and evaluated on 40 held-out participants for the story-versus-math language contrast, achieving mean voxel-map Pearson r=0.642 and Dice AUC=0.519, exceeding compact volumetric BrainSurfCNN-like and SWIFUN-like comparators by Δr=0.0376 and 0.0335 respectively, while raw 95% intervals covered only 4.7% of observed values and five-fold calibration within the held-out cohort raised coverage to 94.8%.