Shutian Lin

Reference genomes for the human skin microbiome have been scarce, especially outside bacteria and across global strain variation. The Global Skin Metagenomic Data resource combined 12,409 newly sequenced and 4,396 public skin metagenomes with 3,077 isolate genomes to reconstruct 452,397 metagenome-assembled genomes and add 42,758 previously uncharacterized taxa. From 1.71 billion predicted protein sequences it consolidated 1,272,886 protein families, 79,434 of which had no homology hit in Pfam or RefSeq.

Reference genomes for the human skin microbiome have been scarce, especially outside bacteria and across global strain variation. The Global Skin Metagenomic Data resource combined 12,409 newly sequenced and 4,396 public skin metagenomes with 3,077 isolate genomes to reconstruct 452,397 metagenome-assembled genomes and add 42,758 previously uncharacterized taxa. From 1.71 billion predicted protein sequences it consolidated 1,272,886 protein families, 79,434 of which had no homology hit in Pfam or RefSeq.