MindRank and Borui Cuanghe team up on cyclic-peptide RDCs: InteraFold-PEP predicts binding modes before any candidate exists
MindRank and Borui Cuanghe have announced a strategic collaboration to advance AI-driven radionuclide drug conjugates (RDCs) that use cyclic peptides as targeting ligands, aimed at unmet needs in precision oncology. MindRank contributes its Intera life-science foundation model system, with InteraFold-PEP predicting how cyclic peptides bind target proteins to guide design, screening and optimization; Borui Cuanghe contributes radiopharmaceutical development, radiolabeling and clinical translation, and the two sides iterate AI design against experimental validation. The target ligands must combine high affinity, high selectivity and good developability, and the work is at the collaboration-launch stage.