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The Journal of asthma : official journal of the Association for the Care of Asthma

Feasibility of Assessing Clinical Remission in Asthma via a Customized Data Extraction Approach from a Real-World Clinical Electronic Medical Records Database in Japan: A Retrospective Real-World Study

Using the Japanese JAMDAS electronic medical records database, this retrospective observational study analyzed 32,258 patients with asthma who initiated fluticasone furoate/umeclidinium/vilanterol single-inhaler triple therapy between August 18, 2020 and December 31, 2024, extracting Asthma Control Test scores via structured query language and hospitalization and emergency transport data via a large language model, and assessed the proportion meeting the Japanese Practical Guidelines for Asthma Management 2024 clinical remission definition (oral corticosteroid-free, no exacerbations, ACT >= 23), treatment patterns, adherence and persistence at 3-month intervals up to 18 months; only 1.8-3.0%, 0.5-1.5% and 4.5-10.