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EuroIntervention

Radial wall strain for residual risk stratification after percutaneous coronary intervention

Using the TARGET All Comers randomised trial of 1,551 patients, this study developed an artificial intelligence algorithm for real-time automated assessment of radial wall strain (RWS) from routine angiography and evaluated its prognostic value in 1,384 non-target vessels from 802 patients, finding that baseline maximal RWS (RWSmax) ≥13% independently predicted the 5-year non-target vessel-oriented composite endpoint (NT-VOCE) with an adjusted hazard ratio of 4.82 (95% CI 3.14-7.40) and an adjusted AUC of 0.73, with the highest predictive accuracy for non-target vessel revascularisation (adjusted AUC 0.92) and even greater performance in the high-quality angiographic image subgroup (adjusted HR 6.89).