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medRxiv

Acceptability of AI-applications in routine clinical care for children and adolescents: perspectives of parents and healthcare professionals

This study investigated AI acceptability among parents (first cohort n = 198; second cohort n = 79) and pediatric healthcare professionals (n = 33) across different disease, diagnosis, or treatment scenarios, finding that more liberal data privacy was associated with reduced willingness to use AI (p < .001), higher perceived disease severity was linked to higher willingness to use AI in the second parent group (beta = .10, p = .013), and when AI and clinician recommendations conflicted, parents were more likely to choose AI over clinician judgment in treatment compared to diagnosis scenarios, with healthcare professionals showing similar patterns but additionally weighting perceived disease severity.