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International Journal of Cardiology

AI-assisted handheld echocardiography for hospital bedside cardiac triage: the prospective OPTIMUST implementation study

OPTIMUST was a prospective, single-center implementation study in which physicians without formal echocardiography certification completed a structured two-month curriculum and performed focused examinations using Caption AI-enabled handheld ultrasound on cardiology and non-cardiology wards; of 287 attempted examinations, 206 (71.8%) were analyzable, operator assessment correlated with expert review of the same handheld image sets for LVEF (r = 0.84), filling-pressure category agreement gave a quadratic weighted κ of 0.659, physicians reported that handheld findings changed or confirmed management in 93.7% of examinations, and 32.8% underwent comprehensive echocardiography within one month.