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Advances in wound care

Admission Red Cell Distribution Width-Albumin Ratio and 1-Year Mortality in Chronic-Wound Inpatients: Prediction-Model Development, Internal Validation, and Exploratory Temporal Evaluation

In a single-center retrospective cohort of 584 adults first admitted for a chronic wound between 2021 and 2024, a two-variable model combining the admission-day red cell distribution width-albumin ratio (RAR) with the age-adjusted Charlson Comorbidity Index (ACCI) predicted 1-year all-cause mortality with an optimism-corrected C-statistic of 0.855 and good calibration, stratifying patients into low-, intermediate-, and high-risk tiers (observed mortality 1.3%, 9.0%, and 36.8%), while discrimination was similar but calibration imprecise in an exploratory temporal evaluation of a later same-center cohort of 124 patients.