Public articles linked to the same research event.
World Journal of Methodology This narrative review summarizes contemporary strategies for managing constipation, encompassing lifestyle and dietary modifications, pharmacological therapies, behavioral interventions, and surgical options for refractory cases, noting that traditional laxatives remain the mainstay while newer agents such as prosecretory drugs, serotonergic agonists, and bile acid modulators have expanded therapeutic possibilities, that non-pharmacological approaches including biofeedback and neuromodulation provide effective alternatives in selected patients, and that substantial methodological variability in clinical trials across diagnostic criteria, endpoints, and follow-up durations limits generalizability, with future research focused on individualized treatment for refractory constipation, surgical
This narrative review summarizes contemporary strategies for managing constipation, encompassing lifestyle and dietary modifications, pharmacological therapies, behavioral interventions, and surgical options for refractory cases, noting that traditional laxatives remain the mainstay while newer agents such as prosecretory drugs, serotonergic agonists, and bile acid modulators have expanded therapeutic possibilities, that non-pharmacological approaches including biofeedback and neuromodulation provide effective alternatives in selected patients, and that substantial methodological variability in clinical trials across diagnostic criteria, endpoints, and follow-up durations limits generalizability, with future research focused on individualized treatment for refractory constipation, surgical
This narrative review summarizes contemporary strategies for managing constipation, encompassing lifestyle and dietary modifications, pharmacological therapies, behavioral interventions, and surgical options for refractory cases, noting that traditional laxatives remain the mainstay while newer agents such as prosecretory drugs, serotonergic agonists, and bile acid modulators have expanded therapeutic possibilities, that non-pharmacological approaches including biofeedback and neuromodulation provide effective alternatives in selected patients, and that substantial methodological variability in clinical trials across diagnostic criteria, endpoints, and follow-up durations limits generalizability, with future research focused on individualized treatment for refractory constipation, surgical
This narrative review summarizes contemporary strategies for managing constipation, encompassing lifestyle and dietary modifications, pharmacological therapies, behavioral interventions, and surgical options for refractory cases, noting that traditional laxatives remain the mainstay while newer agents such as prosecretory drugs, serotonergic agonists, and bile acid modulators have expanded therapeutic possibilities, that non-pharmacological approaches including biofeedback and neuromodulation provide effective alternatives in selected patients, and that substantial methodological variability in clinical trials across diagnostic criteria, endpoints, and follow-up durations limits generalizability, with future research focused on individualized treatment for refractory constipation, surgical